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BLOOD TEST · SMART CARE POLYCLINIC, DEIRA

Bilirubin explained

The yellow pigment the liver clears from blood, reported as a total and a direct fraction.

SAMPLE
Blood
FASTING
Not needed, but usually taken with a fasting panel
INCLUDED IN
Order on its own
WHERE
29 Doha Centre, Al Maktoum Rd, Deira

What the Bilirubin test measures

What is left when old red blood cells break down. The liver processes it so it dissolves, then sends it out in bile. Which of the two fractions is raised is the whole point of measuring both — it separates a harmless inherited pattern from a blockage or liver injury.1

Reported as part of Liver Function Test.

What the result tells you

Total up, direct normal

In a well person this is most often Gilbert's syndrome — a harmless inherited variation needing no treatment, most visible when fasting or run down.

The other cause of that pattern

Faster breakdown of red blood cells, which the blood count helps identify.

Direct fraction raised

This matters more. Bilirubin was processed but cannot get out — pointing at liver cells or an obstruction in the bile ducts. ALP and ALT decide which.

When it becomes visible

Yellowing of the whites of the eyes appears once it rises well above normal. Below that it is silent, which is why it is measured.

How to prepare

Fasting
Not needed, but usually taken with a fasting panel
Best time
Morning, with the rest of the panel
Worth knowing
Prolonged fasting genuinely raises bilirubin in people with Gilbert's syndrome — say so if you fasted longer than asked.

What can move the result

A result outside the usual range does not on its own mean something is wrong. These are the everyday explanations a doctor considers first.

Gilbert's syndrome, common and harmless
Prolonged fasting or recent illness, in people who have it
Faster breakdown of red blood cells
Obstruction of the bile ducts, including gallstones
Liver inflammation from any cause

Frequently asked questions

What is left when old red blood cells break down. The liver processes it so it dissolves, then sends it out in bile. Which of the two fractions is raised is the whole point of measuring both — it separates a harmless inherited pattern from a blockage or liver injury. Total up, direct normal: In a well person this is most often Gilbert's syndrome — a harmless inherited variation needing no treatment, most visible when fasting or run down.

Sources

Written from current guidance and reviewed 31 August 2026.

Sources cited above

  1. Kwo PY, Cohen SM, Lim JK. ACG Clinical Guideline: Evaluation of Abnormal Liver Chemistries. The American Journal of Gastroenterology. 2017;112(1):18-35. PMID 27995906. doi:10.1038/ajg.2016.517The American College of Gastroenterology guideline on what a raised liver enzyme actually means and how an abnormal result should be worked up.

Sources are listed for the specific statements they support. They are published research and guidance, not a substitute for a consultation — what applies to you is decided by a doctor who has assessed you.